Common NameBeta-d-galactose
DescriptionGalactose is an optical isomer of glucose. An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (Galactose-1-phosphate uridyl-transferase deficiency disease) causes an error in galactose metabolism called galactosemia, resulting in elevations of galactose in the blood. Galactose (Gal) (also called brain sugar) is a type of sugar found in dairy products, in sugar beets and other gums and mucilages. It is also synthesized by the body, where it forms part of glycolipids and glycoproteins in several tissues. It is considered a nutritive sweetener because it has food energy. Galactose is less sweet than glucose and not very water-soluble. Galactose is a monosaccharide constituent, together with glucose, of the disaccharide lactose. The hydrolysis of lactose to glucose and galactose is catalyzed by the enzyme beta-galactosidase, a lactase. In the human body, glucose is changed into galactose in order to enable the mammary glands to secrete lactose. Galactan is a polymer of the sugar galactose. It is found in hemicellulose and can be converted to galactose by hydrolysis.
Structure
Molecular FormulaC6H12O6
Average Mass180.15590
Monoisotopic Mass180.06339
IUPAC Name(2R,3R,4S,5R,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Traditional NameΒ-d-galactose
CAS Registry Number7296-64-2
SMILESOC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
InChI IdentifierInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
InChI KeyWQZGKKKJIJFFOK-FPRJBGLDSA-N
CHEBI IDCHEBI:27667
HMDB IDHMDB0003449
StateNot Available
Water Solubility7.82e+02 g/l
logP-2.57
logS0.64
pKa (Strongest Acidic)11.30
pKa (Strongest Basic)-2.98
Hydrogen Acceptor Count6
Hydrogen Donor Count5
Polar Surface Area110.38 Ų
Rotatable Bond Count1
Physiological Charge0
Formal Charge0
Refractivity35.92 m³·mol⁻¹
Polarizability16.33

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