Showing Metabocard for 3-hydroxyindolin-2-one (BASm0001564)
| Common Name | 3-hydroxyindolin-2-one |
|---|---|
| Description | 3-Hydroxy-2-oxoindole is an oxidized indole derivative. Indoles are compounds containing an indole moiety, which consists of pyrrole ring fused to benzene to form 2,3-benzopyrrole. 3-hydroxy-2-oxoindole is a naturally occurring indole metabolite found in human urine (PMID: 11722560 ). It is a reduced form of the more abundant naturally occurring indole metabolite known as isatin (which is derived from the gut microbial metabolism of tryptophan). 3-hydroxy-2-oxoindole is generated via the activity of the enzyme known as isatin reductase, which is found in the liver and kidney (PMID: 11722560 ). It exhibits modest monoamine oxidase A and B inhibitory activity. |
| Structure | |
| Molecular Formula | C8H7NO2 |
| Average Mass | 149.14900 |
| Monoisotopic Mass | 149.04768 |
| IUPAC Name | Not Available |
| Traditional Name | Not Available |
| CAS Registry Number | Not Available |
| SMILES | O=C1Nc2ccccc2C1O |
| InChI Identifier | InChI=1S/C8H7NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4,7,10H,(H,9,11) |
| InChI Key | SGZFJWQQBHYNNF-UHFFFAOYSA-N |
| CHEBI ID | CHEBI:28536 |
| HMDB ID | HMDB0240741 |
| State | Not Available |
| Water Solubility | Not Available |
| logS | Not Available |
| pKa (Strongest Acidic) | Not Available |
| pKa (Strongest Basic) | Not Available |
| Hydrogen Acceptor Count | Not Available |
| Hydrogen Donor Count | Not Available |
| Rotatable Bond Count | Not Available |
| Physiological Charge | Not Available |
| Formal Charge | Not Available |
| Polarizability | Not Available |