Showing Metabocard for L-methionine (R)-S-oxide (BASm0003702)
| Common Name | L-methionine (r)-s-oxide |
|---|---|
| Description | L-Methionine (R)-S-oxide or Met-(R)-O is an oxidized form of methionine. It can be used as a substrate for growth by E. coli. It is known that Escherichia coli methionine mutants can grow on both enantiomers of methionine sulfoxide (met(o)), i.e., Met-R-(O) or Met-S-(O), indicating the presence of enzymes in E. coli that can reduce each of these enantiomers to methionine (met). Recently it was discovered that an enzyme known as fRMsr or L-methionine (R)-S-oxide reductase (EC 1.8.4.14) is the enzyme that catalyzes the chemical reaction L-methionine + thioredoxin disulfide + H2O <=> L-methionine (R)-S-oxide + thioredoxin. It is thought that Met-(R)-O may represent a signaling molecule in response to oxidative stress. [PMID:17535911 ] |
| Structure | |
| Molecular Formula | C5H11NO3S |
| Average Mass | 165.21100 |
| Monoisotopic Mass | 165.04596 |
| IUPAC Name | Not Available |
| Traditional Name | Not Available |
| CAS Registry Number | Not Available |
| SMILES | C[S@@](=O)CC[C@H]([NH3+])C(=O)[O-] |
| InChI Identifier | InChI=1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10+/m0/s1 |
| InChI Key | QEFRNWWLZKMPFJ-ZXPFJRLXSA-N |
| CHEBI ID | CHEBI:58773 |
| MiMeDB ID | MMDBc0031763 |
| State | Expected Solid |
| Water Solubility | Not Available |
| logS | Not Available |
| pKa (Strongest Acidic) | Not Available |
| pKa (Strongest Basic) | Not Available |
| Hydrogen Acceptor Count | Not Available |
| Hydrogen Donor Count | Not Available |
| Rotatable Bond Count | Not Available |
| Physiological Charge | Not Available |
| Formal Charge | Not Available |
| Polarizability | Not Available |